A DFG-funded PhD position (E13, 65%) “Cross-talk and extensive rewiring of CRISPR-Cas systems with the cellular regulatory machinery in Cyanobacteria” is available at Cyanolab immediately

Cyanolab, the Genetics and Experimental Bioinformatics unit at the University of Freiburg, Germany, is searching for a scientist to participate in the DFG-funded Priority Program SPP 2141 “Much more than Defence: The Multiple Functions and Facets of CRISPR-Cas” within the project “Cross-talk and extensive rewiring of CRISPR-Cas systems with the cellular regulatory machinery in Cyanobacteria”. The intended start date is within the last three months of 2018 or early in 2019, or upon negotiation and the position is limited to a duration of 3 years.
For recent relevant publications of our laboratory, see Nature Microbiology 3, 367–377; Trends in Biotechnology 36, 996-1010; Cell Reports (2018) 22, 3377–3384; PLoS ONE (2013), 8(2), e56470.
The project tasks will include the analysis of RNA-protein interactions that have an impact on the prokaryotic immune system, with a focus on the cyanobacterial model organism Synechocystis. The work plan includes the immunoprecipitation, isolation and characterization of ribonucleoprotein complexes, the analysis of transcriptomic datasets and transcription factor binding motifs, the generation and molecular analysis of cyanobacterial mutant strains and the study of intracellular interactions with invader DNA and bacteriophages.
For this we seek a highly motivated candidate with a background in biochemistry, molecular biology or molecular genetics (M.Sc. or diploma level).
The project aims at a fundamental understanding of the interactions between the prokaryotic CRISPR-Cas system and the host cell’s regulatory mechanisms. The work is carried out within an ongoing international collaboration and as part of DFG-funded consortium that involves regular meetings and timely delivery of results. 

Cyanolab is located at the University of Freiburg, located in one of the most beautiful regions of Southern Germany in the heart of Europe. Freiburg is known for its high quality of life at the slopes of the Black Forest, close to the Alps, Switzerland and France. The Faculty of Biology at the University of Freiburg is one of the leading Life Science Departments in the country.

Please send your application by Email to: wolfgang.hess@biologie.uni-freiburg.de
In your application, please include (1) a CV in tabular form, (2) a brief summary of previous research experience and academic qualification, (3) scanned copies of university degrees and (4) contact details for at least one reference.